| Saturday 15th November 2025 The Edward Case Cup 2nd Round North |
||
| Ashton Town | 2-3 | Darwen FC |
| Daisy Hill | P-P | Nelson |
| Postponed due to Ground Issues | ||
| Maghull | 2-2 | Bacup Borough |
| (Maghull won 5-4 on penalties) | ||
| Maine Road | 0-0 | AFC Blackpool |
| (Maine Road won 4-2 on penalties) | ||
| Saturday 15th November 2025 The Edward Case Cup 2nd Round South |
||
| Barnton | 2-0 | Ashville |
| Runcorn Town | 2-1 | Stafford Town |
| Sandbach United | 2-1 | Cheadle Heath Nomads |
| Telford Town | P-P | Stockport Georgians |
| Postponed due to Waterlogged Pitch | ||
| Saturday 15th November 2025 Premier Division |
||
| AFC Liverpool | P-P | Longridge Town |
| Postponed due to Waterlogged Pitch | ||
| Burscough | 1-2 | Glossop North End |
| Chadderton | 8-0 | City of Liverpool |
| Charnock Richard | 5-1 | Cheadle Town |
| FC Isle of Man | 1-3 | West Didsbury & Chorlton |
| Irlam | P-P | Abbey Hey |
| Postponed due to Waterlogged Pitch | ||
| Ramsbottom United | P-P | Pilkington |
| Postponed due to Waterlogged Pitch | ||
| Stockport Town | 2-0 | Barnoldswick Town |
| Wythenshawe | 2-0 | Euxton Villa |
| Saturday 15th November 2025 First Division North |
||
| Ashton Athletic | 3-0 | Garstang |
| Colne | 2-4 | Thornton Cleveleys |
| Squires Gate | 2-1 | Steeton |
| Saturday 15th November 2025 First Division South |
||
| Allscott Heath | 2-2 | Market Drayton Town |
| Foley Meir | 2-1 | Shawbury United |
| Haughmond | P-P | Cammell Laird 1907 |
| Postponed due to Waterlogged Pitch | ||
Saturday KO 15:00, Midweek KO 19:45 unless stated
| Monday 17th November 2025 Cheshire Senior Cup 2nd Round |
| Stockport Town v Warrington Town |
| Tuesday 18th November 2025 Lancashire Challenge Trophy 2nd Round |
| Ashton Athletic v Lancaster City |
| Fulwood Amateurs v AFC Fylde |
| Longridge Town v Daisy Hill |
| Prestwich Heys v Padiham |
| Squires Gate v Nelson |
| Tuesday 18th November 2025 Liverpool Senior Cup Preliminary Round |
| MSB Woolton v Bootle |
| Played at Bootle |
| Tuesday 18th November 2025 Manchester Premier Cup Preliminary Round |
| Ashton United v Chadderton |
| Radcliffe v Irlam |
| Tuesday 18th November 2025 Premier Division |
| Barnoldswick Town v Abbey Hey |
| Cheadle Town v Litherland REMYCA |
| City of Liverpool v Ramsbottom United |
| Glossop North End v FC St Helens |
| Tuesday 18th November 2025 First Division North |
| Holker Old Boys v AFC Blackpool (20:00) |
| Tuesday 18th November 2025 First Division South |
| Ashville v New Mills |
| Sandbach United v Wolverhampton Casuals |
| Tuesday 18th November 2025 Cheshire Senior Cup 2nd Round |
| Runcorn Town v Stockport Georgians |
| Wednesday 19th November 2025 Lancashire Challenge Trophy 2nd Round |
| West Didsbury & Chorlton v Clitheroe |
| Garstang v Wythenshawe (20:00) |
| Wednesday 19th November 2025 The Macron Cup 3rd Round |
| Cammell Laird 1907 v AFC Liverpool |
| Wednesday 19th November 2025 First Division North |
| Darwen FC v Bacup Borough |
| Friday 21st November 2025 The Macron Cup 3rd Round |
| Euxton Villa v Charnock Richard |
| MSB Woolton v Thornton Cleveleys |
| Saturday 22nd November 2025 The Macron Cup 3rd Round |
| Burscough v AFC Blackpool |
| Cheadle Town v Chadderton |
| Ramsbottom United v West Didsbury & Chorlton |
| Sandbach United v Nelson |
| Telford Town v Runcorn Town |
| Saturday 22nd November 2025 Premier Division |
| Longridge Town v FC Isle of Man (13:30) |
| Abbey Hey v Atherton LR |
| Barnoldswick Town v FC St Helens |
| City of Liverpool v Wythenshawe |
| Litherland REMYCA v Stockport Town |
| Pilkington v Padiham |
| Prestwich Heys v Glossop North End |
| South Liverpool v Irlam |
| Saturday 22nd November 2025 First Division North |
| Ashton Town v Fulwood Amateurs |
| Bacup Borough v Squires Gate |
| Garstang v Colne |
| Maghull v Darwen FC |
| Maine Road v Daisy Hill |
| Saturday 22nd November 2025 First Division South |
| Alsager Town v Cheadle Heath Nomads |
| Ashville v Shawbury United |
| Barnton v Eccleshall |
| New Mills v Foley Meir |
| Wolverhampton Sporting Community v Market Drayton Town |
| Premier Division | P | GD | Pts | |
| 1 | West Didsbury & Chorlton | 22 | 28 | 49 |
| 2 | Ramsbottom United | 19 | 32 | 47 |
| 3 | Padiham | 20 | 27 | 47 |
| 4 | Wythenshawe | 18 | 12 | 40 |
| 5 | Burscough | 20 | 13 | 35 |
| 6 | Irlam | 18 | 13 | 34 |
| 7 | FC St Helens | 20 | 11 | 33 |
| 8 | South Liverpool | 19 | 5 | 33 |
| 9 | Chadderton | 17 | 26 | 32 |
| 10 | Longridge Town | 19 | 2 | 28 |
| 11 | Stockport Town | 21 | -3 | 28 |
| 12 | Atherton LR | 18 | 11 | 27 |
| 13 | Glossop North End | 22 | -12 | 26 |
| 14 | Pilkington | 21 | -18 | 26 |
| 15 | Prestwich Heys | 18 | -1 | 24 |
| 16 | Charnock Richard | 19 | 6 | 23 |
| 17 | Cheadle Town | 17 | -4 | 21 |
| 18 | Barnoldswick Town | 18 | -17 | 21 |
| 19 | AFC Liverpool | 19 | -8 | 19 |
| 20 | Euxton Villa | 21 | -15 | 18 |
| 21 | FC Isle of Man | 22 | -27 | 17 |
| 22 | City of Liverpool | 19 | -25 | 16 |
| 23 | Abbey Hey | 19 | -22 | 12 |
| 24 | Litherland REMYCA | 20 | -34 | 4 |
| First Division North | P | GD | Pts | |
| 1 | Maghull | 13 | 12 | 24 |
| 2 | Ashton Town | 13 | 2 | 23 |
| 3 | Nelson | 9 | 1 | 21 |
| 4 | Droylsden | 13 | 8 | 20 |
| 5 | AFC Blackpool | 11 | 7 | 20 |
| 6 | Darwen FC | 12 | 5 | 20 |
| 7 | Bacup Borough | 12 | -1 | 20 |
| 8 | Holker Old Boys | 10 | 10 | 19 |
| 9 | Fulwood Amateurs | 11 | 5 | 18 |
| 10 | Thornton Cleveleys | 13 | 4 | 17 |
| 11 | Daisy Hill | 14 | -2 | 17 |
| 12 | Colne | 13 | -1 | 16 |
| 13 | Steeton | 15 | -7 | 16 |
| 14 | Squires Gate | 14 | -6 | 15 |
| 15 | Maine Road | 13 | 4 | 14 |
| 16 | MSB Woolton | 13 | -7 | 14 |
| 17 | Ashton Athletic | 13 | -13 | 10 |
| 18 | Garstang | 12 | -21 | 8 |
| First Division South | P | GD | Pts | |
| 1 | Runcorn Town | 16 | 33 | 39 |
| 2 | Eccleshall | 15 | 13 | 33 |
| 3 | Telford Town | 15 | 17 | 30 |
| 4 | Barnton | 16 | 12 | 29 |
| 5 | Stockport Georgians | 16 | 12 | 29 |
| 6 | Sandbach United | 15 | 11 | 29 |
| 7 | Stafford Town | 14 | 18 | 27 |
| 8 | New Mills | 15 | 14 | 26 |
| 9 | Foley Meir | 17 | 1 | 25 |
| 10 | Allscott Heath | 16 | 8 | 23 |
| 11 | Ashville | 15 | 5 | 22 |
| 12 | Cheadle Heath Nomads | 17 | -3 | 18 |
| 13 | Alsager Town | 16 | -5 | 17 |
| 14 | Market Drayton Town | 18 | -13 | 15 |
| 15 | Cammell Laird 1907 | 15 | -14 | 15 |
| 16 | Wolverhampton Casuals | 14 | -9 | 14 |
| 17 | Shawbury United | 17 | -30 | 14 |
| 18 | Haughmond | 17 | -29 | 9 |
| 19 | Wolverhampton Sporting Community | 16 | -41 | 5 |
Tables correct as at Sat 15th Nov 2025
