| Wednesday 2nd April 2025 First Division North |
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| Bacup Borough | 0-2 | Maine Road |
| Darwen FC | 4-1 | Ashton Athletic |
| Wednesday 2nd April 2025 First Division South |
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| Eccleshall | 4-0 | Wolverhampton Sporting Community |
| Foley Meir | 2-2 | Alsager Town |
| Tuesday 1st April 2025 First Division North |
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| Atherton LR | 2-0 | Droylsden |
| Euxton Villa | 1-3 | Route One Rovers |
| Holker Old Boys | 2-0 | Garstang |
| Maghull | 0-2 | Ashton Town |
| Skelmersdale United | 0-5 | Daisy Hill |
| Thornton Cleveleys | 1-4 | AFC Blackpool |
| Tuesday 1st April 2025 First Division South |
||
| Market Drayton Town | 3-0 | Sandbach United |
| Runcorn Town | 0-0 | Ashville |
| Shawbury United | 1-1 | Allscott Heath |
| Stafford Town | 0-1 | Abbey Hulton United |
| Stockport Georgians | 3-1 | New Mills |
| Winsford United | 4-0 | Cheadle Heath Nomads |
| Saturday 29th March 2025 The Macron Cup Semi Finals |
||
| AFC Blackpool | 0-2 | Stafford Town |
| Charnock Richard | 1-0 | Barnton |
| Saturday 29th March 2025 First Division North |
||
| Ashton Town | 0-2 | Darwen FC |
| Bacup Borough | 0-1 | Steeton |
| Daisy Hill | 2-2 | Euxton Villa |
| Droylsden | 2-2 | Holker Old Boys |
| Nelson | 0-1 | Atherton LR |
| Route One Rovers | 1-3 | Maghull |
| Skelmersdale United | 0-3 | Thornton Cleveleys |
| Saturday 29th March 2025 First Division South |
||
| Abbey Hulton United | 6-0 | Wolverhampton Sporting Community |
| Ashville | 2-1 | Alsager Town |
| Eccleshall | 3-1 | Market Drayton Town |
| New Mills | 1-2 | Cammell Laird 1907 |
| Runcorn Town | 2-2 | Foley Meir |
| Shawbury United | 0-1 | Sandbach United |
| Stockport Georgians | 0-3 | Winsford United |
Saturday KO 15:00, Midweek KO 19:45 unless stated
| Friday 4th April 2025 Premier Division |
| Chadderton v Pilkington |
| Played at Avro |
| Lower Breck v Litherland REMYCA (20:00) |
| Saturday 5th April 2025 Premier Division |
| AFC Liverpool v West Didsbury & Chorlton |
| Barnoldswick Town v Prestwich Heys |
| Burscough v Longridge Town |
| Bury v Padiham |
| Colne v Cheadle Town |
| FC St Helens v South Liverpool |
| Irlam v Abbey Hey |
| Ramsbottom United v Stockport Town |
| Squires Gate v Glossop North End |
| FC Isle of Man v Charnock Richard (18:00) |
| Saturday 5th April 2025 First Division North |
| Ashton Town v Skelmersdale United (13:00) |
| Ashton Athletic v Route One Rovers |
| Atherton LR v Bacup Borough |
| Garstang v AFC Blackpool |
| Holker Old Boys v Thornton Cleveleys |
| Maghull v Euxton Villa |
| Maine Road v Droylsden |
| Nelson v Daisy Hill |
| Steeton v Darwen FC |
| Saturday 5th April 2025 First Division South |
| Alsager Town v Barnton |
| Cheadle Heath Nomads v Eccleshall |
| Foley Meir v Abbey Hulton United |
| Market Drayton Town v Cammell Laird 1907 |
| New Mills v Allscott Heath |
| Sandbach United v Runcorn Town |
| Shawbury United v Stockport Georgians |
| Winsford United v Ashville |
| Wolverhampton Sporting Community v Stafford Town |
| Premier Division | P | GD | Pts | |
| 1 | Bury | 43 | 72 | 100 |
| 2 | Lower Breck | 43 | 66 | 97 |
| 3 | Ramsbottom United | 43 | 49 | 93 |
| 4 | Padiham | 43 | 37 | 86 |
| 5 | West Didsbury & Chorlton | 43 | 34 | 77 |
| 6 | Irlam * | 43 | 20 | 71 |
| 7 | Chadderton | 43 | 11 | 68 |
| 8 | FC St Helens | 43 | 8 | 64 |
| 9 | AFC Liverpool | 43 | 2 | 64 |
| 10 | Stockport Town | 43 | -1 | 64 |
| 11 | Abbey Hey | 43 | -6 | 62 |
| 12 | FC Isle of Man | 43 | 1 | 61 |
| 13 | Burscough | 43 | -9 | 60 |
| 14 | Charnock Richard | 43 | 8 | 59 |
| 15 | Cheadle Town | 43 | 5 | 58 |
| 16 | Barnoldswick Town | 43 | -10 | 56 |
| 17 | Glossop North End | 43 | -15 | 51 |
| 18 | Longridge Town | 43 | -36 | 45 |
| 19 | Litherland REMYCA | 43 | -26 | 43 |
| 20 | South Liverpool | 43 | -42 | 38 |
| 21 | Pilkington | 43 | -36 | 37 |
| 22 | Colne | 43 | -47 | 33 |
| 23 | Prestwich Heys | 43 | -39 | 30 |
| 24 | Squires Gate | 43 | -46 | 28 |
| First Division North | P | GD | Pts | |
| 1 | Atherton LR | 32 | 41 | 75 |
| 2 | Nelson | 32 | 47 | 70 |
| 3 | Droylsden | 32 | 31 | 66 |
| 4 | Holker Old Boys | 32 | 36 | 62 |
| 5 | Euxton Villa | 32 | 23 | 59 |
| 6 | Darwen FC | 32 | 20 | 55 |
| 7 | Maine Road | 32 | 17 | 48 |
| 8 | Ashton Town | 32 | 5 | 47 |
| 9 | AFC Blackpool * | 32 | 8 | 46 |
| 10 | Daisy Hill | 32 | 6 | 46 |
| 11 | Maghull | 32 | 0 | 44 |
| 12 | Bacup Borough | 32 | 7 | 42 |
| 13 | Ashton Athletic | 32 | -12 | 42 |
| 14 | Thornton Cleveleys | 32 | -19 | 35 |
| 15 | Steeton | 32 | -23 | 32 |
| 16 | Route One Rovers (R) | 32 | -38 | 25 |
| 17 | Garstang (R) | 32 | -55 | 19 |
| 18 | Skelmersdale United (R) | 32 | -94 | 8 |
| First Division South | P | GD | Pts | |
| 1 | Winsford United (C) | 32 | 59 | 80 |
| 2 | Stafford Town | 31 | 48 | 66 |
| 3 | Abbey Hulton United | 32 | 40 | 63 |
| 4 | Sandbach United | 32 | 11 | 61 |
| 5 | Eccleshall | 32 | 11 | 54 |
| 6 | Ashville | 32 | 13 | 50 |
| 7 | Cheadle Heath Nomads | 31 | 8 | 49 |
| 8 | Alsager Town | 32 | 6 | 46 |
| 9 | Stockport Georgians | 32 | -6 | 45 |
| 10 | Cammell Laird 1907 | 32 | 2 | 44 |
| 11 | Market Drayton Town | 32 | 3 | 41 |
| 12 | New Mills | 32 | -6 | 38 |
| 13 | Runcorn Town | 32 | -11 | 36 |
| 14 | Barnton | 32 | -28 | 32 |
| 15 | Foley Meir | 32 | -21 | 30 |
| 16 | Allscott Heath | 32 | -42 | 28 |
| 17 | Shawbury United | 32 | -35 | 24 |
| 18 | Wolverhampton Sporting Community | 32 | -52 | 24 |
Tables correct as at Wed 2nd Apr 2025
