| Tuesday 1st April 2025 | First Division North | ||
| 19:45 |  Atherton LR v Droylsden  | Crilly Park | |
| 19:45 |  Euxton Villa v Route One Rovers  | Jim Fowler Memorial Ground | |
| 19:45 |  Holker Old Boys v Garstang  | The Handmark Engineering Stadium | |
| 19:45 |  Maghull v Ashton Town  | DT Hughes Community Stadium | |
| 19:45 |  Skelmersdale United v Daisy Hill  | The Community Ground | |
| 19:45 |  Thornton Cleveleys v AFC Blackpool  | Gamble Road | |
| Tuesday 1st April 2025 | First Division South | ||
| 19:45 |  Market Drayton Town v Sandbach United  | Greenfields Sports Ground | |
| 19:45 |  Runcorn Town v Ashville  | Viridor Community Stadium | |
| 19:45 |  Shawbury United v Allscott Heath  | Shawbury Utd Community Sports and Recreational Centre | |
| 19:45 |  Stockport Georgians v New Mills  | Cromley Road | |
| 19:45 |  Winsford United v Cheadle Heath Nomads  | Barton Stadium | |
| 20:00 |  Stafford Town v Abbey Hulton United  | Evans Park | |
| Wednesday 2nd April 2025 | First Division North | ||
| 19:45 |  Darwen FC v Ashton Athletic  | Multevo Group Anchor Ground | |
| 20:00 |  Bacup Borough v Maine Road  | Brian Boys West View Stadium | |
| Wednesday 2nd April 2025 | First Division South | ||
| 19:45 |  Eccleshall v Wolverhampton Sporting Community  | Stoke Signage Stadium | |
| 19:45 |  Foley Meir v Alsager Town  | Trentham Foods Stadium | |
| Friday 4th April 2025 | Premier Division | ||
| 19:45 |  Chadderton v Pilkington  | Vestacare Stadium | |
| Played at Avro | |||
| 20:00 |  Lower Breck v Litherland REMYCA  | Anfield Sports Community Centre | |
| Saturday 5th April 2025 | Premier Division | ||
| 15:00 |  AFC Liverpool v West Didsbury & Chorlton  | The Marine Travel Arena | |
| 15:00 |  Barnoldswick Town v Prestwich Heys  | Silentnight Stadium | |
| 15:00 |  Burscough v Longridge Town  | The Community Ground | |
| 15:00 |  Bury v Padiham  | Gigg Lane | |
| 15:00 |  Colne v Cheadle Town  | Haffners Stadium | |
| 15:00 |  FC St Helens v South Liverpool  | SMS PRO SOCCER PARK | |
| 15:00 |  Irlam v Abbey Hey  | The Silver St Stadium | |
| 15:00 |  Ramsbottom United v Stockport Town  | Harry Williams Riverside Stadium | |
| 15:00 |  Squires Gate v Glossop North End  | The Brian Addison Stadium | |
| 18:00 |  FC Isle of Man v Charnock Richard  | The Bowl | |
| Saturday 5th April 2025 | First Division North | ||
| 13:00 | Ashton Town v Skelmersdale United | The Bartons Group Stadium | |
| 15:00 | Ashton Athletic v Route One Rovers | Brocstedes Park | |
| 15:00 | Atherton LR v Bacup Borough | Crilly Park | |
| 15:00 | Garstang v AFC Blackpool | The Riverside | |
| 15:00 | Holker Old Boys v Thornton Cleveleys | The Handmark Engineering Stadium | |
| 15:00 | Maghull v Euxton Villa | DT Hughes Community Stadium | |
| 15:00 | Maine Road v Droylsden | Brantingham Road | |
| 15:00 |  Nelson v Daisy Hill | The Daisy Arena | |
| 15:00 |  Steeton v Darwen FC | Marley Stadium | |
| Saturday 5th April 2025 | First Division South | ||
| 15:00 | Alsager Town v Barnton  | Wood Park | |
| 15:00 | Cheadle Heath Nomads v Eccleshall | Ideal Building Systems Stadium | |
| 15:00 | Foley Meir v Abbey Hulton United | Trentham Foods Stadium | |
| 15:00 | Market Drayton Town v Cammell Laird 1907  | Greenfields Sports Ground | |
| 15:00 | New Mills v Allscott Heath | Church Lane | |
| 15:00 | Sandbach United v Runcorn Town | Sandbach Community Football Centre | |
| 15:00 | Shawbury United v Stockport Georgians | Shawbury Utd Community Sports and Recreational Centre | |
| 15:00 | Winsford United v Ashville | Barton Stadium | |
| 15:00 | Wolverhampton Sporting Community v Stafford Town | Pride Park | |
| Tuesday 8th April 2025 | First Division South | ||
| 20:00 | Stafford Town v Cheadle Heath Nomads | Evans Park | |
| Wednesday 9th April 2025 | West Riding County Cup SF | ||
| 19:45 |  Campion v Route One Rovers | 1st Glass Stadium | |
| Thursday 10th April 2025 | Liverpool Senior Cup SF | ||
| 20:00 | Lower Breck v Runcorn Linnets  | Anfield Sports Community Centre | |
| Friday 11th April 2025 | Premier Division | ||
| 19:45 | Chadderton v Ramsbottom United | Vestacare Stadium | |
| Played at Avro | |||
| 20:00 | AFC Liverpool v Colne | The Marine Travel Arena | |
| Saturday 12th April 2025 | Premier Division | ||
| 15:00 | Abbey Hey v FC St Helens | The Abbey Stadium | |
| 15:00 | Cheadle Town v Bury | The Ground Up Solutions Stadium | |
| 15:00 | Glossop North End v Burscough | The Asgard Engineering Stadium | |
| 15:00 | Lower Breck v Barnoldswick Town | Anfield Sports Community Centre | |
| 15:00 | Padiham v South Liverpool | Ruby Civil Arena | |
| 15:00 | Pilkington v Squires Gate | PSD Stadium | |
| 15:00 | Prestwich Heys v Irlam | Adie Moran Park | |
| 15:00 | Stockport Town v Charnock Richard | Stockport Sports Village | |
| 15:00 | West Didsbury & Chorlton v Longridge Town | Step Places Stadium | |
| 18:00 | FC Isle of Man v Litherland REMYCA | The Bowl | |
| Saturday 12th April 2025 | First Division North | ||
| 15:00 | AFC Blackpool v Atherton LR | Mechanics Ground | |
| 15:00 | Ashton Athletic v Euxton Villa | Brocstedes Park | |
| 15:00 | Daisy Hill v Ashton Town | The Plumb Factory Stadium | |
| 15:00 | Darwen FC v Maine Road | Multevo Group Anchor Ground | |
| 15:00 | Droylsden v Garstang | The Butchers Arms | |
| 15:00 | Maghull v Steeton | DT Hughes Community Stadium | |
| 15:00 | Nelson v Holker Old Boys | The Daisy Arena | |
| 15:00 | Route One Rovers v Thornton Cleveleys | Marley Stadium | |
| 15:00 | Skelmersdale United v Bacup Borough | The Community Ground | |
| Saturday 12th April 2025 | First Division South | ||
| 15:00 | Abbey Hulton United v Ashville | Drayton Beaumont Park | |
| 15:00 | Alsager Town v Winsford United | Wood Park | |
| 15:00 | Barnton v Stockport Georgians | The Creative Hut Stadium | |
| 15:00 | Cammell Laird 1907 v Foley Meir | KRCT LTD STADIUM | |
| 15:00 | Eccleshall v Allscott Heath | Stoke Signage Stadium | |
| 15:00 | New Mills v Market Drayton Town | Church Lane | |
| 15:00 | Shawbury United v Cheadle Heath Nomads | Shawbury Utd Community Sports and Recreational Centre | |
| 15:00 | Stafford Town v Sandbach United | Evans Park | |
| 15:00 | Wolverhampton Sporting Community v Runcorn Town | Pride Park | |
| Tuesday 15th April 2025 | Manchester Premier Cup Final | ||
| 19:45 | Irlam v Hyde United  | Broadhurst Park | |
| Played at FC United of Manchester | |||
| Wednesday 16th April 2025 | Lancashire Challenge Trophy Final | ||
| 19:30 | Bacup Borough v Southport  | The County Ground | |
| Played at The County Ground | |||
| Saturday 19th April 2025 | Premier Division | ||
| 15:00 | Bury v Burscough | Gigg Lane | |
| 15:00 | Chadderton v Litherland REMYCA | The Falcon Fire Stadium | |
| 15:00 | Charnock Richard v Squires Gate | Mossie Park | |
| 15:00 | Cheadle Town v Lower Breck | The Ground Up Solutions Stadium | |
| 15:00 | Colne v Abbey Hey | Haffners Stadium | |
| 15:00 | FC Isle of Man v West Didsbury & Chorlton | The Bowl | |
| 15:00 | Glossop North End v Pilkington | The Asgard Engineering Stadium | |
| 15:00 | Irlam v FC St Helens | The Silver St Stadium | |
| 15:00 | Longridge Town v Prestwich Heys | Longridge Town FC | |
| 15:00 | Ramsbottom United v Barnoldswick Town | Harry Williams Riverside Stadium | |
| 15:00 | South Liverpool v AFC Liverpool | Jericho Lane | |
| 15:00 | Stockport Town v Padiham | Stockport Sports Village | |
| Saturday 19th April 2025 | First Division Champions Cup Final | ||
| 15:00 |  TBC v TBC | Club with better record | |
| Saturday 19th April 2025 | First Division Champions Cup Final | ||
| 15:00 | TBC v TBC | Club with better record | |
| Saturday 19th April 2025 | First Division North Play Offs SF | ||
| 15:00 | 2nd place v 5th place | 2nd place | |
| 15:00 | 3rd place v 4th place | 3rd place | |
| Saturday 19th April 2025 | First Division South Play Offs SF | ||
| 15:00 | 2nd place v 5th place | 2nd place | |
| 15:00 | 3rd place v 4th place | 3rd place | |
| Monday 21st April 2025 | The Edward Case Cup Final | ||
| 15:00 | Atherton LR v Stafford Town | SMS PRO SOCCER PARK | |
| Played at FC St Helens | |||
| Tuesday 1st April 2025 First Division North |
| Atherton LR v Droylsden (19:45) |
| Euxton Villa v Route One Rovers (19:45) |
| Holker Old Boys v Garstang (19:45) |
| Maghull v Ashton Town (19:45) |
| Skelmersdale United v Daisy Hill (19:45) |
| Thornton Cleveleys v AFC Blackpool (19:45) |
| Tuesday 1st April 2025 First Division South |
| Market Drayton Town v Sandbach United (19:45) |
| Runcorn Town v Ashville (19:45) |
| Shawbury United v Allscott Heath (19:45) |
| Stockport Georgians v New Mills (19:45) |
| Winsford United v Cheadle Heath Nomads (19:45) |
| Stafford Town v Abbey Hulton United (20:00) |
| Wednesday 2nd April 2025 First Division North |
| Darwen FC v Ashton Athletic (19:45) |
| Bacup Borough v Maine Road (20:00) |
| Wednesday 2nd April 2025 First Division South |
| Eccleshall v Wolverhampton Sporting Community (19:45) |
| Foley Meir v Alsager Town (19:45) |
| Friday 4th April 2025 Premier Division |
|
| Chadderton v Pilkington (19:45) | |
| Played at Avro | |
| Lower Breck v Litherland REMYCA (20:00) | |
| Saturday 5th April 2025 Premier Division |
| AFC Liverpool v West Didsbury & Chorlton (15:00) |
| Barnoldswick Town v Prestwich Heys (15:00) |
| Burscough v Longridge Town (15:00) |
| Bury v Padiham (15:00) |
| Colne v Cheadle Town (15:00) |
| FC St Helens v South Liverpool (15:00) |
| Irlam v Abbey Hey (15:00) |
| Ramsbottom United v Stockport Town (15:00) |
| Squires Gate v Glossop North End (15:00) |
| FC Isle of Man v Charnock Richard (18:00) |
| Saturday 5th April 2025 First Division North |
| Ashton Town v Skelmersdale United (13:00) |
| Ashton Athletic v Route One Rovers (15:00) |
| Atherton LR v Bacup Borough (15:00) |
| Garstang v AFC Blackpool (15:00) |
| Holker Old Boys v Thornton Cleveleys (15:00) |
| Maghull v Euxton Villa (15:00) |
| Maine Road v Droylsden (15:00) |
| Nelson v Daisy Hill (15:00) |
| Steeton v Darwen FC (15:00) |
| Saturday 5th April 2025 First Division South |
| Alsager Town v Barnton (15:00) |
| Cheadle Heath Nomads v Eccleshall (15:00) |
| Foley Meir v Abbey Hulton United (15:00) |
| Market Drayton Town v Cammell Laird 1907 (15:00) |
| New Mills v Allscott Heath (15:00) |
| Sandbach United v Runcorn Town (15:00) |
| Shawbury United v Stockport Georgians (15:00) |
| Winsford United v Ashville (15:00) |
| Wolverhampton Sporting Community v Stafford Town (15:00) |
| Tuesday 8th April 2025 First Division South |
| Stafford Town v Cheadle Heath Nomads (20:00) |
| Wednesday 9th April 2025 West Riding County Cup Semi Finals |
| Campion v Route One Rovers (19:45) |
| Thursday 10th April 2025 Liverpool Senior Cup Semi Finals |
| Lower Breck v Runcorn Linnets (20:00) |
| Friday 11th April 2025 Premier Division |
|
| Chadderton v Ramsbottom United (19:45) | |
| Played at Avro | |
| AFC Liverpool v Colne (20:00) | |
| Saturday 12th April 2025 Premier Division |
| Abbey Hey v FC St Helens (15:00) |
| Cheadle Town v Bury (15:00) |
| Glossop North End v Burscough (15:00) |
| Lower Breck v Barnoldswick Town (15:00) |
| Padiham v South Liverpool (15:00) |
| Pilkington v Squires Gate (15:00) |
| Prestwich Heys v Irlam (15:00) |
| Stockport Town v Charnock Richard (15:00) |
| West Didsbury & Chorlton v Longridge Town (15:00) |
| FC Isle of Man v Litherland REMYCA (18:00) |
| Saturday 12th April 2025 First Division North |
| AFC Blackpool v Atherton LR (15:00) |
| Ashton Athletic v Euxton Villa (15:00) |
| Daisy Hill v Ashton Town (15:00) |
| Darwen FC v Maine Road (15:00) |
| Droylsden v Garstang (15:00) |
| Maghull v Steeton (15:00) |
| Nelson v Holker Old Boys (15:00) |
| Route One Rovers v Thornton Cleveleys (15:00) |
| Skelmersdale United v Bacup Borough (15:00) |
| Saturday 12th April 2025 First Division South |
| Abbey Hulton United v Ashville (15:00) |
| Alsager Town v Winsford United (15:00) |
| Barnton v Stockport Georgians (15:00) |
| Cammell Laird 1907 v Foley Meir (15:00) |
| Eccleshall v Allscott Heath (15:00) |
| New Mills v Market Drayton Town (15:00) |
| Shawbury United v Cheadle Heath Nomads (15:00) |
| Stafford Town v Sandbach United (15:00) |
| Wolverhampton Sporting Community v Runcorn Town (15:00) |
| Tuesday 15th April 2025 Manchester Premier Cup Final |
|
| Irlam v Hyde United (19:45) | |
| Played at FC United of Manchester | |
| Wednesday 16th April 2025 Lancashire Challenge Trophy Final |
|
| Bacup Borough v Southport (19:30) | |
| Played at The County Ground | |
| Saturday 19th April 2025 Premier Division |
| Bury v Burscough (15:00) |
| Chadderton v Litherland REMYCA (15:00) |
| Charnock Richard v Squires Gate (15:00) |
| Cheadle Town v Lower Breck (15:00) |
| Colne v Abbey Hey (15:00) |
| FC Isle of Man v West Didsbury & Chorlton (15:00) |
| Glossop North End v Pilkington (15:00) |
| Irlam v FC St Helens (15:00) |
| Longridge Town v Prestwich Heys (15:00) |
| Ramsbottom United v Barnoldswick Town (15:00) |
| South Liverpool v AFC Liverpool (15:00) |
| Stockport Town v Padiham (15:00) |
| Saturday 19th April 2025 First Division Champions Cup Final |
| TBC v TBC (15:00) |
| Saturday 19th April 2025 First Division Champions Cup Final |
| TBC v TBC (15:00) |
| Saturday 19th April 2025 First Division North Play Offs Semi Finals |
| 2nd place v 5th place (15:00) |
| 3rd place v 4th place (15:00) |
| Saturday 19th April 2025 First Division South Play Offs Semi Finals |
| 2nd place v 5th place (15:00) |
| 3rd place v 4th place (15:00) |
| Monday 21st April 2025 The Edward Case Cup Final |
|
| Atherton LR v Stafford Town (15:00) | |
| Played at FC St Helens | |
