| Sat 26/07/25 | Euxton Villa v Prestwich Heys | 1-1 |  | | | | | |
| Tue 29/07/25 | Euxton Villa v Longridge Town | 1-1 | | | | | | |
| Sat 02/08/25 | City of Liverpool v Euxton Villa (CUP) | 2-1 | | | | | | |
| Sat 09/08/25 | West Didsbury & Chorlton v Euxton Villa | 3-3 | | | |  | | |
| Tue 12/08/25 | Padiham v Euxton Villa | 2-0 | | | | | | |
| Sat 16/08/25 | Euxton Villa v Barnoldswick Town | 2-3 | | | | | | |
| Sat 23/08/25 | Euxton Villa v Worsbrough Bridge Athletic (CUP) * | 2-1 | | | | | | |
| Mon 25/08/25 | Euxton Villa v Litherland REMYCA | 3-2 | | | | | | |
| Sat 30/08/25 | Stockport Town v Euxton Villa | 1-1 | | | | | | |
| Fri 05/09/25 | Euxton Villa v FC St Helens | 1-2 | | | | | |  |
| Tue 09/09/25 | Euxton Villa v Burscough | 0-1 | | | | | | |
| Sat 13/09/25 | Euxton Villa v Irlam | 2-1 | | | | | | |
| Tue 16/09/25 | Chadderton v Euxton Villa | 2-2 | | | | | | |
| Sat 20/09/25 | Euxton Villa v Sandbach United (CUP) | 3-3 | | | | | | |
| Tue 23/09/25 | Euxton Villa v Ramsbottom United | 0-4 | | | | | | |
| Fri 26/09/25 | Euxton Villa v Holker Old Boys (CUP) * | 5-0 | |  | | | | |
| Sat 04/10/25 | Abbey Hey v Euxton Villa | 1-2 | | | | | | |
| Wed 15/10/25 | South Liverpool v Euxton Villa | 1-1 | | | | | | |
| Sat 18/10/25 | Euxton Villa v Carlisle City (CUP) | 1-1 | | | | | | |
| Tue 21/10/25 | Burscough v Euxton Villa | 3-0 | | | | | | |
| Sat 25/10/25 | Euxton Villa v Cheadle Town | 1-1 | | | | | | |
| Tue 04/11/25 | Euxton Villa v FC Isle of Man | 3-3 | | | | | | |
| Sat 08/11/25 | Longridge Town v Euxton Villa | 4-3 | | | | | | |
| Tue 11/11/25 | Euxton Villa v AFC Liverpool | 0-3 | | | | | | |
| Sat 15/11/25 | Wythenshawe v Euxton Villa | 2-0 | | | | | | |
| Fri 21/11/25 | Euxton Villa v Charnock Richard (CUP) | 3-3 | | | | | | |
